diff --git a/src/transmute/transmute.py b/src/transmute/transmute.py
index 402af73..c6c04ee 100644
--- a/src/transmute/transmute.py
+++ b/src/transmute/transmute.py
@@ -196,15 +196,29 @@ class Transmute:
             return None
         self._run_gem_transmutes()
 
+    def check_cube_empty(self) -> bool:
+        self.open_cube()
+        area = self.inspect_cube()
+        self.close_cube()
+        return area.count_empty() == 12
+
+    def inspect_cube(self)-> InventoryCollection:
+        return self.inspect_area(4, 3, roi=Config.ui_roi["cube_area_roi"], known_items=FLAWLESS_GEMS)
+    
     def _run_gem_transmutes(self) -> None:
         Logger.info("Starting gem transmute")
         self._last_game = self._game_stats._game_counter
         s = self.inspect_stash()
         algorithm = SimpleGemPicking(s)
         inventory = self.inspect_inventory_area(FLAWLESS_GEMS)
+        is_cube_empty = None
         while True:
             while inventory.count_empty() >= 3:
-                next_batch = algorithm.next_batch()
+                next_batch = algorithm.next_batch()                
+                is_cube_empty = self.check_cube_empty() if is_cube_empty is None else is_cube_empty
+                if not is_cube_empty:
+                    Logger.warning("Some items detected in the cube. Skipping transmute")
+                    break
                 if next_batch is None:
                     Logger.info("No more gems to cube")
                     break